(Ivanhoe Newswire) – Adding another perk to the list of why exercising is beneficial, scientists found that physical activity improves arthritis symptoms even when remaining on a high-fat diet.
The insight suggests that excess weight alone isn't what causes the aches and pains of osteoarthritis, despite the long-held notion that carrying extra pounds strains the joints and leads to the inflammatory condition.
"What's surprising is that exercise, without substantial weight loss, can be beneficial to the joints," Farshid Guilak, Ph.D., professor of orthopaedic surgery at Duke and senior author of the study, was quoted as saying. "Ideally, it would be best to be fit and lose a little weight, but this shows that exercise alone can improve the health of your joints."
Many cases of arthritis are associated with obesity and inactivity, so the Duke researchers set out to determine whether a high fat diet induces knee osteoarthritis, and then whether exercise provides a protective effect.
Using two sets of male mice – half fed a high-fat diet and the other fed regular chow – the researchers noted significant differences among the two groups. The mice on the high-fat food gained weight rapidly, processed glucose poorly and had much higher blood levels of molecules that trigger the chronic inflammation associated with osteoarthritis.
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The insight suggests that excess weight alone isn't what causes the aches and pains of osteoarthritis, despite the long-held notion that carrying extra pounds strains the joints and leads to the inflammatory condition.
"What's surprising is that exercise, without substantial weight loss, can be beneficial to the joints," Farshid Guilak, Ph.D., professor of orthopaedic surgery at Duke and senior author of the study, was quoted as saying. "Ideally, it would be best to be fit and lose a little weight, but this shows that exercise alone can improve the health of your joints."
Many cases of arthritis are associated with obesity and inactivity, so the Duke researchers set out to determine whether a high fat diet induces knee osteoarthritis, and then whether exercise provides a protective effect.
Using two sets of male mice – half fed a high-fat diet and the other fed regular chow – the researchers noted significant differences among the two groups. The mice on the high-fat food gained weight rapidly, processed glucose poorly and had much higher blood levels of molecules that trigger the chronic inflammation associated with osteoarthritis.
read more...
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